All functions

build_dtl_bern()

Build a multi-stage drop-the-losers multi-arm clinical trial for a Bernoulli distributed primary outcome

build_dtl_norm()

Build a multi-stage drop-the-losers multi-arm clinical trial for a normally distributed primary outcome

build_dtl_pois()

Build a multi-stage drop-the-losers multi-arm clinical trial for a Poisson distributed primary outcome

build_gs_bern()

Build a multi-stage group-sequential multi-arm clinical trial for a Bernoulli distributed primary outcome

build_gs_norm()

Build a multi-stage group-sequential multi-arm clinical trial for a normally distributed primary outcome

build_gs_pois()

Build a multi-stage group-sequential multi-arm clinical trial for a Poisson distributed primary outcome

build_ss_bern()

Build a single-stage multi-arm clinical trial for a Bernoulli distributed primary outcome

build_ss_norm()

Build a single-stage multi-arm clinical trial for a normally distributed primary outcome

build_ss_pois()

Build a single-stage multi-arm clinical trial for a Poisson distributed primary outcome

des_dtl_bern()

Design a multi-stage drop-the-losers multi-arm clinical trial for a Bernoulli distributed primary outcome

des_dtl_norm()

Design a multi-stage drop-the-losers multi-arm clinical trial for a normally distributed primary outcome

des_dtl_pois()

Design a multi-stage drop-the-losers multi-arm clinical trial for a Poisson distributed primary outcome

des_gs_bern()

Design a multi-stage group-sequential multi-arm clinical trial for a Bernoulli distributed primary outcome

des_gs_norm()

Design a multi-stage group-sequential multi-arm clinical trial for a normally distributed primary outcome

des_gs_pois()

Design a multi-stage group-sequential multi-arm clinical trial for a Poisson distributed primary outcome

des_ss_bern()

Design a single-stage multi-arm clinical trial for a Bernoulli distributed primary outcome

des_ss_norm()

Design a single-stage multi-arm clinical trial for a normally distributed primary outcome

des_ss_pois()

Design a single-stage multi-arm clinical trial for a Poisson distributed primary outcome

gui()

Graphical user interface to multi-arm trial design determination

multiarm

multiarm: Design of single- and multi-stage multi-arm clinical trials

opchar_dtl_bern()

Analytically determine the operating characteristics of a multi-stage drop-the-losers multi-arm clinical trial for a Bernoulli distributed primary outcome

opchar_dtl_norm()

Analytically determine the operating characteristics of a multi-stage drop-the-losers multi-arm clinical trial for a normally distributed primary outcome

opchar_dtl_pois()

Analytically determine the operating characteristics of a multi-stage drop-the-losers multi-arm clinical trial for a Poisson distributed primary outcome

opchar_gs_bern()

Analytically determine the operating characteristics of a multi-stage group-sequential multi-arm clinical trial for a Bernoulli distributed primary outcome

opchar_gs_norm()

Analytically determine the operating characteristics of a multi-stage group-sequential multi-arm clinical trial for a normally distributed primary outcome

opchar_gs_pois()

Analytically determine the operating characteristics of a multi-stage group-sequential multi-arm clinical trial for a Poisson distributed primary outcome

opchar_ss_bern()

Analytically determine the operating characteristics of a single-stage multi-arm clinical trial for a Bernoulli distributed primary outcome

opchar_ss_norm()

Analytically determine the operating characteristics of a single-stage multi-arm clinical trial for a normally distributed primary outcome

opchar_ss_pois()

Analytically determine the operating characteristics of a single-stage multi-arm clinical trial for a Poisson distributed primary outcome

plot(<multiarm_des_dtl_bern>)

Plot operating characteristics of a multi-stage drop-the-losers multi-arm clinical trial for a Bernoulli distributed primary outcome

plot(<multiarm_des_dtl_norm>)

Plot operating characteristics of a multi-stage drop-the-losers multi-arm clinical trial for a normally distributed primary outcome

plot(<multiarm_des_dtl_pois>)

Plot operating characteristics of a multi-stage drop-the-losers multi-arm clinical trial for a Poisson distributed primary outcome

plot(<multiarm_des_gs_bern>)

Plot operating characteristics of a multi-stage group-sequential multi-arm clinical trial for a Bernoulli distributed primary outcome

plot(<multiarm_des_gs_norm>)

Plot operating characteristics of a multi-stage group-sequential multi-arm clinical trial for a normally distributed primary outcome

plot(<multiarm_des_gs_pois>)

Plot operating characteristics of a multi-stage group-sequential multi-arm clinical trial for a Poisson distributed primary outcome

plot(<multiarm_des_ss_bern>)

Plot operating characteristics of a single-stage multi-arm clinical trial for a Bernoulli distributed primary outcome

plot(<multiarm_des_ss_norm>)

Plot operating characteristics of a single-stage multi-arm clinical trial for a normally distributed primary outcome

plot(<multiarm_des_ss_pois>)

Plot operating characteristics of a single-stage multi-arm clinical trial for a Poisson distributed primary outcome

sim_dtl_bern()

Empirically determine the operating characteristics of a multi-stage drop-the-losers multi-arm clinical trial for a Bernoulli distributed primary outcome

sim_dtl_norm()

Empirically determine the operating characteristics of a multi-stage drop-the-losers multi-arm clinical trial for a normally distributed primary outcome

sim_dtl_pois()

Empirically determine the operating characteristics of a multi-stage drop-the-losers multi-arm clinical trial for a Poisson distributed primary outcome

sim_gs_bern()

Empirically determine the operating characteristics of a multi-stage group-sequential multi-arm clinical trial for a Bernoulli distributed primary outcome

sim_gs_norm()

Empirically determine the operating characteristics of a multi-stage group-sequential multi-arm clinical trial for a normally distributed primary outcome

sim_gs_pois()

Empirically determine the operating characteristics of a multi-stage group-sequential multi-arm clinical trial for a Poisson distributed primary outcome

sim_ss_bern()

Empirically determine the operating characteristics of a single-stage multi-arm clinical trial for a Bernoulli distributed primary outcome

sim_ss_norm()

Empirically determine the operating characteristics of a single-stage multi-arm clinical trial for a normally distributed primary outcome

sim_ss_pois()

Empirically determine the operating characteristics of a single-stage multi-arm clinical trial for a Poisson distributed primary outcome